Free USMLE Pharmacology Questions bank for Step 1 2024

17 July 2024 | Written & Fact-checked by

Test your preparation with our Free USMLE Pharmacology questions bank for Step 1

Question banks are really important while preparing for any exam. They not only give you valuable insights into the type of test ahead but also give you the opportunity to test your preparation. That is why are working on bringing a free USMLE Pharmacology questions bank for you.

Pharmacology questions constitute a significant portion of the USMLE Step 1 exam, typically accounting for 15-22% of the total test. This emphasis reflects the critical role pharmacological knowledge plays in medical practice, as physicians must possess a thorough understanding of drug mechanisms to effectively diagnose and treat patients.

Test takers can expect questions that assess their comprehension of drug classifications, mechanisms of action, pharmacokinetics, and pharmacodynamics.

Additionally, questions may evaluate candidates’ ability to apply pharmacological principles to clinical scenarios, emphasizing the integration of basic science knowledge with clinical reasoning.

Mastery of pharmacology is therefore essential for success on the Step 1 exam and our Free USMLE Pharmacology questions bank for Step 1 is here for you to practice.

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1) A 32-year-old female presents with complaints of muscle weakness, particularly affecting the ocular and bulbar muscles. The weakness fluctuates throughout the day and improves with rest. She mentions difficulty in swallowing and occasional double vision. The healthcare provider considers prescribing Neostigmine to enhance neuromuscular transmission. How does it enhance neuromuscular transmission?

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2) A 30-year-old patient undergoes surgery with general anesthesia. The surgical procedure involves the administration of a high concentration of inhalational anaesthetics. Following the surgery, the patient experiences a transient period of increased breathlessness, confusion, dizziness, and nausea. The symptoms resolve spontaneously within a few minutes. Which inhalational anaesthetic is the most likely cause of these symptoms?

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3) A 50-year-old patient is brought to the coronary care unit in emergency. The patient's current vital signs include a heart rate of 140 beats per minute, blood pressure of 110/70 mmHg, and the ECG reveals a regular narrow QRS complex tachycardia consistent with supraventricular arrhythmia. The healthcare provider decides to initiate beta-blocker therapy with Esmolol. Why is Esmolol preferred in this case?

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4) A 28-year-old female presents to the emergency department with complaints of fever, dysuria, and lower abdominal pain. Urinalysis reveals pyuria, and the diagnosis of uncomplicated cystitis is made. The healthcare provider decides to prescribe a sulfonamide for the treatment of this infection. Which enzyme is primarily targeted by sulfonamides to exert their antibacterial effect?

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5) A 45-year-old male with a history of chronic obstructive pulmonary disease (COPD) develops an exacerbation of his respiratory symptoms. The healthcare provider decides to prescribe an antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Which class of antibiotics is the most likely choice in this situation?

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HOW TO STUDY PHARMACOLOGY FOR USMLE STEP 1?

Here we have a few frequently asked questions regarding, How to study Pharmacology for USMLE?

How should I approach studying Pharmacology for USMLE Step 1?

You should utilize a combination of resources such as textbooks, review books, online lectures, and question banks to reinforce your understanding of pharmacological concepts.

Are there specific study strategies that can help with Pharmacology preparation?

You must try to use active learning techniques such as spaced repetition, flashcards, and concept mapping to reinforce key concepts. Additionally, practice applying pharmacological principles to clinical vignettes to enhance your problem-solving skills.

Is it necessary to review specific drug classes more thoroughly than others?

Although it’s important to have a broad understanding of all drug classes, prioritize high-yield drug classes such as antibiotics, cardiovascular agents, psychopharmacology, and chemotherapy agents.

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